Shaping mechanisms of metal specificity in a family of metazoan metallothioneins: evolutionary differentiation of mollusc metallothioneins
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چکیده
منابع مشابه
Metal-binding mechanisms in metallothioneins.
Metallothionein are small, cysteine-rich, metal-binding proteins that are found ubiquitously in nature. Most metallothioneins bind multiple metals in two well-defined metal-thiolate clusters. This perspective discusses the use of optical spectroscopy to study the metalation of metallothioneins and the emergence of electrospray ionization mass spectrometry as a means of studying the mechanism of...
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113Cd-NMR studies have established that vertebrate and invertebrate metallothioneins contain two unique metal-thiolate clusters. However, it proved to be difficult to account theoretically for all features of the 113Cd-NMR spectra. In a reinvestigation of these features using chromatographically homogeneous 113Cd7-metallothionein we have identified a total of seven 113Cd resonances and have con...
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Metal ions are essential for growth, but in excess, these compounds can become highly toxic. Both plants and animals have adapted numerous ways to maintain metal homeostasis while mitigating detrimental effects of excess metals ions, including the metalchelating proteins metallothionein (MT) and phytochelatin. Although phytochelatins have been shown to play an important role in the detoxificati...
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ساموئل بکت بیشتر از هر نویسنده دیگری در نیم? دوم قرن بیستم با گفتارش زمان? ما را به آستان? از هم پاشیدگی کشانده است، آستانه ای که در آن مدرنیته با سرانجام گریزان اما غیرقابل اجتناب خود مواجه می شود. در این تحقیق روی مفهوم فردیت و محو آن در دوران پسامدرن تاکید شده و در طی آن سعی شده است که فردیت مدرن و پسامدرن در رمان های سه گانه بکت بررسی گردد. تحقیق حاضر یک بررسی کتابخانه ای و کیفی بر روی سه ر...
15 صفحه اولDossier Metallothioneins ■ Metallothioneins in the clam Ruditapes decussatus : an overview
The clam R. decussatus is a suspension-feeding bivalve mollusc widely distributed in European and Mediterranean coastal waters. Due to its economic importance it is extensively cultured in many countries, and particularly in Portugal where its production represents > 80 % of total shellfish production. The selection of the clam R. decussatus as a bioindicator was a consequence of its economic i...
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ژورنال
عنوان ژورنال: BMC Biology
سال: 2011
ISSN: 1741-7007
DOI: 10.1186/1741-7007-9-4